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Shape variation of bilayer membrane daughter vesicles induced by anisotropic membrane inclusions

Cellular & Molecular Biology Letters volume 11, pages 90–101 (2006)Cite this article

Abstract

A theoretical model of a two-component bilayer membrane was used in order to describe the influence of anisotropic membrane inclusions on shapes of membrane daughter micro and nano vesicles. It was shown that for weakly anisotropic inclusions the stable vesicle shapes are only slightly out-of-round. In contrast, for strongly anisotropic inclusions the stable vesicle shapes may significantly differ from spheres, i.e. they have a flattened oblate shape at small numbers of inclusions in the membrane, and an elongated cigar-like prolate shape at high numbers of inclusions in the vesicle membrane.

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Affiliations

  1. Laboratory of Physics, Faculty of Electrical Engineering, University of Ljubljana, Tržaška 25, SI-1000, Ljubljana, Slovenia

    Klemen Bohinc, Darko Lombardo, Veronika Kraljiglič, Miha Fošnarič, Franjo Pernuš & Aleš Iglič

  2. University College for Health Studies, University of Ljubljana, Poljanska 26a, SI-1000, Ljubljana, Slovenia

    Klemen Bohinc

  3. Institute of Biophysics, Faculty of Medicine, University of Ljubljana, Lipičeva 2, 1000, Ljubljana, Slovenia

    Veronika Kraljiglič

  4. Department of Physics, North Dakota State University, Fargo, ND, 58105-5566, USA

    Sylvio May

  5. Department of Biology, Åbo Akademi University, Abo/Turku, FIN-20520, Finland

    Henry Hägerstrand

Authors
  1. Klemen Bohinc
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  2. Darko Lombardo
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  3. Veronika Kraljiglič
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  4. Miha Fošnarič
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  5. Sylvio May
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  6. Franjo Pernuš
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  7. Henry Hägerstrand
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  8. Aleš Iglič
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Correspondence to Aleš Iglič.

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Bohinc, K., Lombardo, D., Kraljiglič, V. et al. Shape variation of bilayer membrane daughter vesicles induced by anisotropic membrane inclusions. Cell. Mol. Biol. Lett. 11, 90–101 (2006). https://doi.org/10.2478/s11658-006-0009-3

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  • DOI: https://doi.org/10.2478/s11658-006-0009-3

Key words

  • Bilayer membranes
  • Daughter vesicles
  • Anisotropic membrane inclusions

Cellular & Molecular Biology Letters

ISSN: 1689-1392

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