High level expression of STAG1/PMEPA1 in an androgen-independent prostate cancer PC3 subclone
Cellular & Molecular Biology Letters volume 12, pages 370–377 (2007)
In this paper, we describe the isolation and characterization of two PC3 subclones. One subclone, mr, showed an epithelial phenotype, the other, M1, showed a sarcomatous morphology. Transplanted into nude mice, mr developed tumors at a dramatically faster rate than M1. Comparing the two subclones, differentially expressed genes were identified, including E-cadherin, IL-8 and STAG1/PMEPA1. These genes were expressed at higher levels in mr than in M1.
prostate specific antigen
solid tumor associated gene 1
short tandem repeat
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Hirokawa, Y.S., Takagi, A., Uchida, K. et al. High level expression of STAG1/PMEPA1 in an androgen-independent prostate cancer PC3 subclone. Cell Mol Biol Lett 12, 370–377 (2007). https://doi.org/10.2478/s11658-007-0009-y
- Prostate cancer cell line