Open Access

The effect of growth medium on the antioxidant defense of Saccharomyces cerevisiae

Cellular & Molecular Biology LettersAn International Journal200712:17

https://doi.org/10.2478/s11658-007-0017-y

Received: 12 January 2007

Accepted: 20 February 2007

Published: 15 March 2007

Abstract

We compared the oxidation of dihydrorhodamine 123, glutathione contents and activities of superoxide dismutase (SOD) and catalase for three wild-type strains of Saccharomyces cerevisiae grown on media with different carbon sources. The rate of oxidation of dihydrorhodamine 123 was much higher in respiring cells grown on ethanol or glycerol media than in fermenting cells grown on glucose medium. The total SOD activity was highest on glycerol medium and lowest on ethanol medium, while the catalase activity was highest on glycerol medium. The sequence of glutathione content values was: glucose > ethanol > glycerol.

Key words

Yeast Saccharomyces cerevisiae Reactive oxygen species Superoxide dismutase Catalase Glutathione

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