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  • Research Article
  • Open Access

On the role of ball and chain interactions in recovery from the inactivation of the shaker potassium channel

Cellular & Molecular Biology LettersAn International Journal200813:526

  • Received: 1 October 2007
  • Accepted: 29 January 2008
  • Published:


We describe a new factor in the recovery from inactivation in the ball and chain model. We propose a model in which the tension from the chain may help pull the ball away from its binding site, reducing the duration of the inactivation period. A corresponding model was built and analysed.

Key words

  • Ion channels
  • Inactivation
  • Recovery from inactivation
  • Ball and chain model