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Fig. 3 | Cellular & Molecular Biology Letters

Fig. 3

From: The in vitro effects of a novel estradiol analog on cell proliferation and morphology in human epithelial cervical carcinoma

Fig. 3

PlasDIC images of HeLa cells demonstrating the morphological changes induced by ESE-16. a and b Cells propagated in growth medium (a) and vehicle-treated control cells (b) were confluent, with majority of cells in interphase. c ESE-16-treated cells: several cells are blocked in metaphase and there are visible apoptotic characteristics such as shrunken cells and apoptotic bodies. d Hallmarks of apoptosis were observed in the positive control cells, which were exposed to actinomycin D (20× magnification)

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