Fig. 5
![Fig. 5](http://media.springernature.com/full/springer-static/image/art%3A10.1186%2Fs11658-019-0148-y/MediaObjects/11658_2019_148_Fig5_HTML.png)
MIR4435-2HG regulates HCC cell proliferation through miRNA-487a. Compared with control (C) and negative control (NC) groups, overexpression of MIR4435-2HG and miRNA-487a led to the promoted proliferation of cells of HCC cell lines. In addition, miRNA-487a knockdown led to the inhibited proliferation of cells of HCC cell lines and partially attenuated the enhancing effects of MIR4435-2HG overexpression on cancer cell proliferation. *p < 0.05