Fig. 2From: Burn-induced heterotopic ossification from incidence to therapy: key signaling pathways underlying ectopic bone formationSchematic diagram showing the signaling pathways and mediators involved in burn-induced HO. Current evidence for mechanisms directly involved in burn-induced HO suggests four main pathways: vessel- and endothelial cell-based pathways; immune cell-based pathways; muscle satellite cell-based pathways; and other factorsBack to article page