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  1. Arachidonic acid 15-lipoxygenases (ALOX15) play a role in mammalian erythropoiesis but they have also been implicated in inflammatory processes. Seven intact Alox genes have been detected in the mouse reference g...

    Authors: Florian Reisch, Dagmar Heydeck, Marjann Schäfer, Michael Rothe, Jiaxing Yang, Sabine Stehling, Gerhard P. Püschel and Hartmut Kuhn
    Citation: Cellular & Molecular Biology Letters 2023 28:97
    Content type: Brief Report Published on:

  2. PSA is a type of proto-oncogene that is specifically and highly expressed in embryonic and prostate cancer cells, but not expressed in normal prostate tissue cells. The specific expression of prostate-specific an...

    Authors: Yi Yang, Hongbing Mei, Xiaohong Han, Xintao Zhang, Jianli Cheng, Zhongfu Zhang, Han Wang and Haixia Xu
    Citation: Cellular & Molecular Biology Letters 2023 28:96
    Content type: Brief Report Published on:

  3. Long-term exposure of humans to air pollution is associated with an increasing risk of cardiovascular diseases (CVDs). Astaxanthin (AST), a naturally occurring red carotenoid pigment, was proved to have multip...

    Authors: Jingyi Ren, Bowen Yin, Zihao Guo, Xiaoya Sun, Huanting Pei, Rui Wen, Ziyi Wang, Siqi Zhu, Jinshi Zuo, Yadong Zhang and Yuxia Ma
    Citation: Cellular & Molecular Biology Letters 2023 28:95
    Content type: Research Article Published on:

  5. Periostin is an extracellular matrix protein that plays a critical role in cell fate determination and tissue remodeling, but the underlying role and mechanism of periostin in diabetic cardiomyopathy (DCM) are...

    Authors: Qing-Bo Lu, Xiao Fu, Yao Liu, Zi-Chao Wang, Shi-Yi Liu, Yu-Chao Li and Hai-Jian Sun
    Citation: Cellular & Molecular Biology Letters 2023 28:93
    Content type: Research Article Published on:

  6. Hypervirulent Klebsiella pneumoniae (hvKp) infection-induced sepsis-associated acute lung injury (ALI) has emerged as a significant clinical challenge. Increasing evidence suggests that activated inflammatory mac...

    Authors: Yihan Xu, Chunying Zhang, Danni Cai, Rongping Zhu and Yingping Cao
    Citation: Cellular & Molecular Biology Letters 2023 28:92
    Content type: Research Article Published on:

  8. The pulmonary surfactant that lines the air–liquid surface within alveoli is a protein–lipid mixture essential for gas exchange. Surfactant lipids and proteins are synthesized and stored in the lamellar body (...

    Authors: Wenqin Xu, Xiaocui Ma, Qing Wang, Jingjing Ye, Nengqian Wang, Zhenzhen Ye and Tianbing Chen
    Citation: Cellular & Molecular Biology Letters 2023 28:90
    Content type: Research Article Published on:

  9. The unique expression pattern endows oncofetal genes with great value in cancer diagnosis and treatment. However, only a few oncofetal genes are available for clinical use and the underlying mechanisms that dr...

    Authors: Yiqing Zhu, Bang Xiao, Meng Liu, Meiting Chen, Ningqi Xia, Haiyan Guo, Jinfeng Huang, Zhiyong Liu and Fang Wang
    Citation: Cellular & Molecular Biology Letters 2023 28:89
    Content type: Research Published on:

  10. The musculoskeletal system supports the movement of the entire body and provides blood production while acting as an endocrine organ. With aging, the balance of bone homeostasis is disrupted, leading to bone l...

    Authors: Xu He, Wei Hu, Yuanshu Zhang, Mimi Chen, Yicheng Ding, Huilin Yang, Fan He, Qiaoli Gu and Qin Shi
    Citation: Cellular & Molecular Biology Letters 2023 28:88
    Content type: Mini Review Published on:

  11. Mitochondrial transfer regulates intercellular communication, and mitochondria regulate cell metabolism and cell survival. However, the role and mechanism of mitochondrial transfer in Cd-induced nonalcoholic f...

    Authors: Jian Sun, Yan Chen, Tao Wang, Waseem Ali, Yonggang Ma, Yan Yuan, Jianhong Gu, Jianchun Bian, Zongping Liu and Hui Zou
    Citation: Cellular & Molecular Biology Letters 2023 28:87
    Content type: Research Article Published on:

  12. Membrane rafts play a crucial role in the regulation of many important biological processes. Our previous data suggest that specific interactions of flotillins with MPP1 are responsible for membrane raft domai...

    Authors: Magdalena Trybus, Anita Hryniewicz-Jankowska, Karolina Wójtowicz, Tomasz Trombik, Aleksander Czogalla and Aleksander F. Sikorski
    Citation: Cellular & Molecular Biology Letters 2023 28:86
    Content type: Research Published on:

  13. Ubiquitin–proteasome-system-mediated clearance of misfolded proteins is essential for cells to maintain proteostasis and reduce the proteotoxicity caused by these aberrant proteins. When proteasome activity is...

    Authors: Chenliang Zhang, YiChun Duan, Chen Huang and Liping Li
    Citation: Cellular & Molecular Biology Letters 2023 28:85
    Content type: Research Article Published on:

  15. Zinc finger protein X-linked (ZFX) has been shown to promote the growth of tumor cells, including leukemic cells. However, the role of ZFX in the growth and drug response of chronic myeloid leukemia (CML) stem...

    Authors: Xiuyan Zhang, Yu Wang, Jinchang Lu, Lun Xiao, Hui Chen, Quanxue Li, Yuan-Yuan Li, Peng Xu, Changgeng Ruan, Haixia Zhou and Yun Zhao
    Citation: Cellular & Molecular Biology Letters 2023 28:83
    Content type: Research Published on:

  17. Early and prompt reperfusion therapy has markedly improved the survival rates among patients enduring myocardial infarction (MI). Nonetheless, the resulting adverse remodeling and the subsequent onset of heart...

    Authors: Wenjie Zuo, Renhua Sun, Zhenjun Ji and Genshan Ma
    Citation: Cellular & Molecular Biology Letters 2023 28:81
    Content type: Review Published on:

  18. The mitochondrial gene MCCC2, a subunit of the heterodimer of 3-methylcrotonyl-CoA carboxylase, plays a pivotal role in catabolism of leucine and isovaleric acid. The molecular mechanisms and prognostic value ...

    Authors: Wanjun Liu, Si Chen, Wenqing Xie, Qian Wang, Qianxin Luo, Minghan Huang, Minyi Gu, Ping Lan and Daici Chen
    Citation: Cellular & Molecular Biology Letters 2023 28:80
    Content type: Research Published on:

  19. Lupus nephritis (LN) is associated with significant mortality and morbidity, while effective therapeutics and biomarkers are limited since the pathogenesis is complex. This study investigated the roles of the ...

    Authors: Huimeng Qi, Zhaoguo Zheng and Qiang Liu
    Citation: Cellular & Molecular Biology Letters 2023 28:79
    Content type: Research Published on:

  20. N6-methyladenosine (m6A) modification is a dynamic, reversible process and is the most prevalent internal modification of RNA. This modification is regulated by three protein groups: methyltransferases (“writers”...

    Authors: Xiaoyue Zhang, Qiu Peng and Lujuan Wang
    Citation: Cellular & Molecular Biology Letters 2023 28:78
    Content type: Review Letter Published on:

  21. Hepatic fibrosis is a common consequence of chronic liver diseases without approved antifibrotic therapies. Long noncoding RNAs (lncRNAs) play an important role in various pathophysiological processes. However...

    Authors: Xiaohui Han, Beichen Guo, Sicong Zhao, Yehua Li, Jing Zhu, Yifan He, Jiajun Wang, Qingbin Yao, Shuai Shao, Lina Zheng, Zhemin Shi, Tao Han, Wei Hong and Kun Zhang
    Citation: Cellular & Molecular Biology Letters 2023 28:77
    Content type: Research Published on:

  22. During aging and after traumatic injuries, cartilage and bone cells are exposed to various pathophysiologic mediators, including reactive oxygen species (ROS), damage-associated molecular patterns, and proinfl...

    Authors: Jana Riegger, Astrid Schoppa, Leonie Ruths, Melanie Haffner-Luntzer and Anita Ignatius
    Citation: Cellular & Molecular Biology Letters 2023 28:76
    Content type: Review Published on:

  23. Osteoarthritis (OA), a common joint disorder with articular cartilage degradation as the main pathological change, is the major source of pain and disability worldwide. Despite current treatments, the overall ...

    Authors: Zehao Zhang, Sheng Zhao, Zhaofeng Sun, Chuanxing Zhai, Jiang Xia, Caining Wen, Yuge Zhang and Yuanmin Zhang
    Citation: Cellular & Molecular Biology Letters 2023 28:75
    Content type: Review Letter Published on:

  24. Cardiomyocyte death induced by autophagy inhibition is an important cause of cardiac dysfunction. In-depth exploration of its mechanism may help to improve cardiac dysfunction. In our previous study, we found ...

    Authors: Xiaoyan Zhi, Shu Shi, Yang Li, Mingxia Ma, Yaolin Long, Chen Li, Haihu Hao, Huirong Liu, Xiaohui Wang and Li Wang
    Citation: Cellular & Molecular Biology Letters 2023 28:74
    Content type: Research Published on:

  25. Cancer remains a significant global health challenge, necessitating the exploration of novel and more precise therapeutic options beyond conventional treatments. In this regard, clustered regularly interspaced...

    Authors: Mingxia Wang, Menghui Chen, Xia Wu, Xinbo Huang and Bo Yu
    Citation: Cellular & Molecular Biology Letters 2023 28:73
    Content type: Review Letter Published on:

  26. In recent years, N6-methyladenosine (m6A) methylation modification of mRNA has been studied extensively. It has been reported that m6A determines mRNA fate and participates in many cellular functions and reaction...

    Authors: Huan Li, Jun Zhao, Hao Deng, YuCheng Zhong, Mian Chen, LinSheng Chi, GuoQun Luo, Cong Cao, Cong Yu, Honghai Liu and Xinzong Zhang
    Citation: Cellular & Molecular Biology Letters 2023 28:72
    Content type: Research Letter Published on:

  27. Mechanical pressure overload and other stimuli often contribute to heart hypertrophy, a significant factor in the induction of heart failure. The UDP-glucose ceramide glycosyltransferase (UGCG) enzyme plays a ...

    Authors: Shengyu Cui, Xutao Zhang, Yuhua Li, Shan Hu, Bing Wu, Zhao Fang, Jixian Gao, Ming Li, Haoliang Wu, Bo Tao, Hao Xia and Lin Xu
    Citation: Cellular & Molecular Biology Letters 2023 28:71
    Content type: Research Published on:

  28. Chronic apical periodontitis is a prevalent oral disease characterized by bone loss, and its underlying mechanisms remain unclear. This study aimed to investigate the role and mechanism of the serine protease ...

    Authors: Tingting Jia, Fang Yuan, Jingqiao Tao, Gang Wang, Xianhua Zhang, Bin Zhang and Hongbo Li
    Citation: Cellular & Molecular Biology Letters 2023 28:70
    Content type: Research Letter Published on:

  29. Authors: Yanchun Li, Bing Xu, Xueying Ren, Luyang Wang, Yaqing Xu, Yefeng Zhao, Chen Yang, Chen Yuan, Huanjuan Li, Xiangmin Tong, Ying Wang and Jing Du
    Citation: Cellular & Molecular Biology Letters 2023 28:69
    Content type: Correction Published on:

    The original article was published in Cellular & Molecular Biology Letters 2022 27:81

  30. Desmocollin-1 (DSC1) is a desmosomal transmembrane glycoprotein that maintains cell-to-cell adhesion. DSC1 was previously associated with lymph node metastasis of luminal A breast tumors and was found to incre...

    Authors: Petr Lapcik, Petr Sulc, Lucia Janacova, Katerina Jilkova, David Potesil, Pavla Bouchalova, Petr Müller and Pavel Bouchal
    Citation: Cellular & Molecular Biology Letters 2023 28:68
    Content type: Research Letter Published on:

  31. Prenatal infection has been implicated in the development of neuropsychiatric disorders in children. We hypothesised that exposure to lipopolysaccharide during prenatal development could induce anxiety-like be...

    Authors: Chie-Pein Chen, Pei-Chun Chen, Yu-Ling Pan and Yi-Chao Hsu
    Citation: Cellular & Molecular Biology Letters 2023 28:67
    Content type: Research Published on:

  32. Endothelial dysfunction and deregulated microRNAs (miRNAs) participate in the development of sepsis and are associated with septic organ failure and death. Here, we explored the role of miR-15b-5p on inflammat...

    Authors: Elisa Martino, Nunzia D’Onofrio, Anna Balestrieri, Luigi Mele, Celestino Sardu, Raffaele Marfella, Giuseppe Campanile and Maria Luisa Balestrieri
    Citation: Cellular & Molecular Biology Letters 2023 28:66
    Content type: Research Published on:

  33. Peripheral nerve damage causes neuroinflammation, which plays a critical role in establishing and maintaining neuropathic pain (NeP). The mechanisms contributing to neuroinflammation remain poorly elucidated, ...

    Authors: Jingyi Du, Nan Cheng, Yifan Deng, Ping Xiang, Jianfen Liang, Zhenye Zhang, Ziqing Hei and Xiang Li
    Citation: Cellular & Molecular Biology Letters 2023 28:65
    Content type: Research Published on:

  34. In plants, RNase III Dicer-like proteins (DCLs) act as sensors of dsRNAs and process them into short 21- to 24-nucleotide (nt) (s)RNAs. Plant DCL4 is involved in the biogenesis of either functional endogenous ...

    Authors: Paola Leonetti, Arianna Consiglio, Dennis Arendt, Ralph Peter Golbik, Luisa Rubino, Torsten Gursinsky, Sven-Erik Behrens and Vitantonio Pantaleo
    Citation: Cellular & Molecular Biology Letters 2023 28:64
    Content type: Research Letter Published on:

  35. Nitrogen (N), phosphorus (P) and potassium (K) are critical macronutrients in crops, such that deficiency in any of N, P or K has substantial effects on crop growth. However, the specific commonalities of plan...

    Authors: Ying Fu, Annaliese S. Mason, Maolin Song, Xiyuan Ni, Lei Liu, Jianghua Shi, Tanliu Wang, Meili Xiao, Yaofeng Zhang, Donghui Fu and Huasheng Yu
    Citation: Cellular & Molecular Biology Letters 2023 28:63
    Content type: Research Letter Published on:

  36. Bladder cancer (BLCA) is a malignancy that frequently metastasizes and leads to poor patient prognosis. It is essential to understand the molecular mechanisms underlying the progression and metastasis of BLCA ...

    Authors: Xiangqin Kuang, Zhuojun Zhang, Difeng Li, Wenhao Bao, Jinyuan Pan, Ping Zhou, Han Chen, Zhiqing Gao, Xiaoyi Xie, Chunxiao Yang, Ge Zhu, Zhongqiu Zhou, Ruiming Tang, Zhengfu Feng, Lihuan Zhou, Xiaoli Feng…
    Citation: Cellular & Molecular Biology Letters 2023 28:62
    Content type: Research Published on:

  37. Amphibian derived pro-healing peptides as molecular probes might provide a promising strategy for development of drug candidates and elucidation of cellular and molecular mechanisms of skin wound healing. A no...

    Authors: Chao Li, Zhe Fu, Tao Jin, Yixiang Liu, Naixin Liu, Saige Yin, Zhuo Wang, Yubing Huang, Yinglei Wang, Yingxuan Zhang, Jiayi Li, Yutong Wu, Li He, Jing Tang, Ying Wang and Xinwang Yang
    Citation: Cellular & Molecular Biology Letters 2023 28:61
    Content type: Research Published on:

  38. Sebaceous glands (SGs) synthesize and secret sebum to protect and moisturize the dermal system via the complicated endocrine modulation. Dysfunction of SG are usually implicated in a number of dermal and infla...

    Authors: Tao Yang, Renyi Hei, Xiaosong Li, Tianhua Ma, Yifen Shen, Chao Liu, Wen He, Lin Zhu, Yongchun Gu, Yanping Hu, Wenbin Wei and Yihang Shen
    Citation: Cellular & Molecular Biology Letters 2023 28:60
    Content type: Research Letter Published on:

  39. The dynamics of phosphatidylserine in the plasma membrane is a tightly regulated feature of eukaryotic cells. Phosphatidylserine (PS) is found preferentially in the inner leaflet of the plasma membrane. Disrup...

    Authors: Eimina Dirvelyte, Daina Bujanauskiene, Evelina Jankaityte, Neringa Daugelaviciene, Ugne Kisieliute, Igor Nagula, Rima Budvytyte and Urte Neniskyte
    Citation: Cellular & Molecular Biology Letters 2023 28:59
    Content type: Research Published on:

  40. One of the factors that affect the progression of melanoma is the tumor microenvironment, which consists of cellular elements, extracellular matrix, acidification, and a hypoxic state. Adipocytes are one of th...

    Authors: Aleksandra Simiczyjew, Justyna Wądzyńska, Katarzyna Pietraszek-Gremplewicz, Magdalena Kot, Marcin Ziętek, Rafał Matkowski and Dorota Nowak
    Citation: Cellular & Molecular Biology Letters 2023 28:58
    Content type: Research Published on:

  41. The preference for glucose oxidative mode has crucial impacts on various physiological activities, including determining stem cell fate. External mechanical factors can play a decisive role in regulating criti...

    Authors: Zijie Zhang, Shuyue Cui, Yajing Fu, Jixiao Wang, Jiani Liu and Fulan Wei
    Citation: Cellular & Molecular Biology Letters 2023 28:57
    Content type: Research Published on:

  42. Focal adhesions (FAs) are integrin-containing, multi-protein structures that link intracellular actin to the extracellular matrix and trigger multiple signaling pathways that control cell proliferation, differ...

    Authors: Marija Lončarić, Nikolina Stojanović, Anja Rac-Justament, Kaatje Coopmans, Dragomira Majhen, Jonathan D. Humphries, Martin J. Humphries and Andreja Ambriović-Ristov
    Citation: Cellular & Molecular Biology Letters 2023 28:56
    Content type: Research Letter Published on:

  43. Hepatic ischemia–reperfusion injury (IRI) in donation after cardiac death (DCD) donors is a major determinant of transplantation success. Endoplasmic reticulum (ER) stress plays a key role in hepatic IRI, with...

    Authors: Pengpeng Yue, Xiaoyan Lv, Jian You, Yongkang Zou, Jun luo, Zhongshan Lu, Hankun Cao, Zhongzhong Liu, Xiaoli Fan and Qifa Ye
    Citation: Cellular & Molecular Biology Letters 2023 28:55
    Content type: Research Published on:

  44. The AMPA-type ionotropic glutamate receptor mediates fast excitatory neurotransmission in the brain. A variety of auxiliary subunits regulate its gating properties, assembly, and trafficking, but it is unknown...

    Authors: Chenlu Yu, Hendrik F. P. Runge, Antara Mukhopadhyay, Gerd Zolles and Maximilian H. Ulbrich
    Citation: Cellular & Molecular Biology Letters 2023 28:54
    Content type: Research Letter Published on:

  45. Fibulin-like extracellular matrix protein 2 (EFEMP2) has been reported to be related to the progression of various cancers. We have previously reported that EFEMP2 was highly expressed in ovarian cancer and wa...

    Authors: Xin Shen, Xuli Jin, Shuang Fang and Jie Chen
    Citation: Cellular & Molecular Biology Letters 2023 28:53
    Content type: Research Published on:

  46. Improvements in treatment and chemotherapy have increased the survival rate of osteosarcoma, but overall efficacy remains low, highlighting the need for new gene therapy methods. Clustered regularly interspace...

    Authors: Yawei Hu, Hao Zhang, Zengfeng Guo, Jianhua Zhou, Wang Zhang, Ming Gong and Jiawen Wu
    Citation: Cellular & Molecular Biology Letters 2023 28:52
    Content type: Research Letter Published on:

  47. The NOD-like receptor protein 3 (NLRP3) inflammasome is a protein complex that regulates innate immune responses by activating caspase-1 and the inflammatory cytokines interleukin (IL)-1β and IL-18. Multiple s...

    Authors: Ying Chen, Xingyan Ye, Germaine Escames, Wangrui Lei, Xin Zhang, Meng Li, Tong Jing, Yu Yao, Zhenye Qiu, Zheng Wang, Darío Acuña-Castroviejo and Yang Yang
    Citation: Cellular & Molecular Biology Letters 2023 28:51
    Content type: Review Letter Published on:

  48. Energy metabolism disorder or insufficient energy supply during incubation will affect the development and survival of avian embryos. Especially, β-oxidation could not provide the continuous necessary energy f...

    Authors: Heng Wang, Wenqi Liang, Xuyang Wang, Yuchun Zhan, Wence Wang, Lin Yang and Yongwen Zhu
    Citation: Cellular & Molecular Biology Letters 2023 28:50
    Content type: Research Letter Published on:

  49. Transfer (t)RNA-derived small RNA (tsRNA), generated from precursor or mature tRNA, is a new type of small non-coding RNA (sncRNA) that has recently been shown to play a vital role in human cancers. However, i...

    Authors: Rui Zhao, Zhenming Yang, Bo Zhao, Wenjing Li, Yaohui Liu, Xiaoxue Chen, Jing Cao, Jiarui Zhang, Yan Guo, Licheng Xu, Jinpeng Wang, Yanan Sun, Ming Liu and Linli Tian
    Citation: Cellular & Molecular Biology Letters 2023 28:49
    Content type: Research Letter Published on:

  50. Pulmonary fibrosis is a major category of end-stage changes in lung diseases, characterized by lung epithelial cell damage, proliferation of fibroblasts, and accumulation of extracellular matrix. Peroxiredoxin...

    Authors: Hu-Nan Sun, Chen-Xi Ren, Dong Hun Lee, Wei-Hao Wang, Xiao-Yu Guo, Ying-Ying Hao, Xiao-Ming Wang, Hui-Na Zhang, Wan-Qiu Xiao, Nan Li, Jie Cong, Ying-Hao Han and Taeho Kwon
    Citation: Cellular & Molecular Biology Letters 2023 28:48
    Content type: Research Published on:

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