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  1. MicroRNAs (miRNAs) are fundamental post-transcriptional modulators of several critical cellular processes, a number of which are involved in host defense mechanisms. In particular, miRNA let-7 functions as an ...

    Authors: Arash Letafati, Sajad Najafi, Mehran Mottahedi, Mohammad Karimzadeh, Ali Shahini, Setareh Garousi, Mohammad Abbasi-Kolli, Javid Sadri Nahand, Seyed Saeed Tamehri Zadeh, Michael R. Hamblin, Neda Rahimian, Mohammad Taghizadieh and Hamed Mirzaei
    Citation: Cellular & Molecular Biology Letters 2022 27:14
  2. In recent years, morbidity and mortality of prostate cancer (PCa) have increased dramatically, while mechanistic understanding of its onset and progression remains unmet. LncRNA SNHG3 has been proved to stimul...

    Authors: Xiaotian Wang, Yongsheng Song, Yaxing Shi, Da Yang, Jiaxing Li and Bo Yin
    Citation: Cellular & Molecular Biology Letters 2022 27:13
  3. The ERp57/PDIA3 protein is a pleiotropic member of the PDIs family and, although predominantly located in the endoplasmic reticulum (ER), has indeed been found in other cellular compartments, such as the nucle...

    Authors: Silvia Chichiarelli, Fabio Altieri, Giuliano Paglia, Elisabetta Rubini, Marco Minacori and Margherita Eufemi
    Citation: Cellular & Molecular Biology Letters 2022 27:12
  4. The novel coronavirus disease 2019 (COVID-19) pandemic has spread worldwide, and finding a safe therapeutic strategy and effective vaccine is critical to overcoming severe acute respiratory syndrome coronaviru...

    Authors: Hamidreza Zalpoor, Abdullatif Akbari, Azam Samei, Razieh Forghaniesfidvajani, Monireh Kamali, Azadeh Afzalnia, Shirin Manshouri, Fatemeh Heidari, Majid Pornour, Majid Khoshmirsafa, Hossein Aazami and Farhad Seif
    Citation: Cellular & Molecular Biology Letters 2022 27:10
  5. Bladder cancer is the fourth most common malignancy in males. It can present across the whole continuum of severity, from mild through well-differentiated disease to extremely malignant tumours with poor survi...

    Authors: M. Kanmalar, Siti Fairus Abdul Sani, Nur Izzahtul Nabilla B. Kamri, Nur Akmarina B. M. Said, Amirah Hajirah B. A. Jamil, S. Kuppusamy, K. S. Mun and D. A. Bradley
    Citation: Cellular & Molecular Biology Letters 2022 27:9
  6. Glycosyltransferases play a crucial role in various cancers. β1, 3-N-acetylglucosaminyltransferase 2, a polylactosamine synthase, is an important member of the glycosyltransferase family. However, the biological ...

    Authors: Zhiguo Luo, Qing Hu, Yuanhui Tang, Yahui Leng, Tian Tian, Shuangyue Tian, Chengyang Huang, Ao Liu, Xinzhou Deng and Li Shen
    Citation: Cellular & Molecular Biology Letters 2022 27:8
  7. Canonical Wnt/β-catenin signaling is a complex cell-communication mechanism that has a central role in the progression of various cancers. The cellular factors that participate in the regulation of this signal...

    Authors: Hongjuan You, Qi Li, Delong Kong, Xiangye Liu, Fanyun Kong, Kuiyang Zheng and Renxian Tang
    Citation: Cellular & Molecular Biology Letters 2022 27:7
  8. Coronavirus disease 2019 (COVID-19), which is caused by severe acute respiratory syndrome coronavirus-2 (SARS-CoV-2), is associated with a high mortality rate. The majority of deaths in this disease are caused...

    Authors: Mohammad Rafi Khezri, Reza Varzandeh and Morteza Ghasemnejad-Berenji
    Citation: Cellular & Molecular Biology Letters 2022 27:6
  9. Osteosarcoma (OS) is a common primary bone malignancy. Long noncoding RNA HCG18 is known to play an important role in a variety of cancers. However, its role in OS and relevant molecular mechanisms are unclear.

    Authors: Xiaohui Pan, Jin Guo, Canjun Liu, Zhanpeng Pan, Zhicheng Yang, Xiang Yao and Jishan Yuan
    Citation: Cellular & Molecular Biology Letters 2022 27:5
  10. Leaf senescence is an integral part of plant development and is driven by endogenous cues such as leaf or plant age. Developmental senescence aims to maximize the usage of carbon, nitrogen and mineral resource...

    Authors: Ulrike Zentgraf, Ana Gabriela Andrade-Galan and Stefan Bieker
    Citation: Cellular & Molecular Biology Letters 2022 27:4
  11. Calcitriol (an active metabolite of vitamin D) modulates the expression of hundreds of human genes by activation of the vitamin D nuclear receptor (VDR). However, VDR-mediated transcriptional modulation does n...

    Authors: Anna M. Olszewska, Adam K. Sieradzan, Piotr Bednarczyk, Adam Szewczyk and Michał A. Żmijewski
    Citation: Cellular & Molecular Biology Letters 2022 27:3
  12. Sestrins (Sesns), highly conserved stress-inducible metabolic proteins, are known to protect organisms against various noxious stimuli including DNA damage, oxidative stress, starvation, endoplasmic reticulum ...

    Authors: Yitong Chen, Tingben Huang, Zhou Yu, Qiong Yu, Ying Wang, Ji’an Hu, Jiejun Shi and Guoli Yang
    Citation: Cellular & Molecular Biology Letters 2022 27:2
  13. Chemotherapeutic drugs are used to treat advanced stages of cancer or following surgery. However, cancers often develop resistance against drugs, leading to failure of treatment and recurrence of the disease. ...

    Authors: Parisa Maleki Dana, Fatemeh Sadoughi, Zatollah Asemi and Bahman Yousefi
    Citation: Cellular & Molecular Biology Letters 2022 27:1
  14. This study evaluated microRNA-148a-3p in esophageal carcinoma cells. The prediction of bioinformatics analysis revealed that microRNA-148a-3p may target CEP55. qRT-PCR and western blot showed that CEP55 level ...

    Authors: Yong Lin, Yushan Chen, Rongqiang Shen, Dingzhu Chen and Yimin Lin
    Citation: Cellular & Molecular Biology Letters 2021 26:54
  15. Since the discovery of the first MDM2 inhibitors, we have gained deeper insights into the cellular roles of MDM2 and p53. In this review, we focus on MDM2 inhibitors that bind to the p53-binding domain of MDM2...

    Authors: Lucia Haronikova, Ondrej Bonczek, Pavlina Zatloukalova, Filip Kokas-Zavadil, Martina Kucerikova, Philip J. Coates, Robin Fahraeus and Borivoj Vojtesek
    Citation: Cellular & Molecular Biology Letters 2021 26:53
  16. Ovarian cancer is a devastating gynecological malignancy and frequently presents as an advanced carcinoma with disseminated peritoneum metastasis. Acacetin exerts anti-cancerous effects in several carcinomas. ...

    Authors: Meng Tian, Yingjie Tang, Ting Huang, Yang Liu and Yingzheng Pan
    Citation: Cellular & Molecular Biology Letters 2021 26:51
  17. Esterase D (ESD) is a nonspecific esterase that detoxifies formaldehyde. Many reports have stated that ESD activity is associated with a variety of physiological and pathological processes. However, the detail...

    Authors: Yuejun Yang, Xinpeng Chen, Wen Yao, Xiaoling Cui, Na Li, ZhaoMin Lin, Baoxiang Zhao and Junying Miao
    Citation: Cellular & Molecular Biology Letters 2021 26:50
  18. Hepatocellular carcinoma (HCC) is now the second leading cause of cancer death worldwide and lacks effectual therapy due to its high rate of tumor recurrence and metastasis. The aim of this study was to invest...

    Authors: Ying Xing, Yang Liu, Zhong Qi, Zhengrong Liu, Xin Wang and Hongyi Zhang
    Citation: Cellular & Molecular Biology Letters 2021 26:49
  19. Intestinal mucositis is a common side effect of chemotherapy and radiotherapy. Very few drugs can efficiently ameliorate it. Tertiary butylhydroquinone (TBHQ) is a widely used food preservative with known immu...

    Authors: Shihua Deng, Dongming Wu, Li Li, Jin Li and Ying Xu
    Citation: Cellular & Molecular Biology Letters 2021 26:48
  20. Owing to an increase in the aging population, osteoporosis has become a severe public health concern, with a high prevalence among the elderly and postmenopausal adults. Osteoporosis-related fracture is a majo...

    Authors: Xiao-Yu He, Hai-Ming Yu, Shu Lin and Yi-Zhong Li
    Citation: Cellular & Molecular Biology Letters 2021 26:47
  21. Epigenetics refers to nucleotide sequence-independent events, and heritable changes, including DNA methylation and histone modification (as the two main processes), contributing to the phenotypic features of t...

    Authors: Raheleh Halabian, Valizadeh Arshad, Ali Ahmadi, Pardis Saeedi, Sadegh Azimzadeh Jamalkandi and Mohammad Reza Alivand
    Citation: Cellular & Molecular Biology Letters 2021 26:46

    The Correction to this article has been published in Cellular & Molecular Biology Letters 2022 27:78

  22. Liquid–liquid phase separation (LLPS) within the nucleus is directly linked to driving gene expression through transcriptional complexes. Histone lysine methyltransferase 2D (KMT2D) is widely present in many c...

    Authors: Weihan Li, Lei Wu, Hui Jia, Zenghua Lin, Renhao Zhong, Yukun Li, Chenwei Jiang, Shifan Liu, Xiaorong Zhou and Erhao Zhang
    Citation: Cellular & Molecular Biology Letters 2021 26:45
  23. Various types of normal and cancer cells undergo senescence in response to carboplatin and paclitaxel, which are considered the gold standard treatments in ovarian cancer management. Surprisingly, the effect o...

    Authors: Paweł Uruski, Agnieszka Sepetowska, Corinna Konieczna, Martyna Pakuła, Michał Wyrwa, Akylbek Tussupkaliyev, Andrzej Tykarski, Justyna Mikuła-Pietrasik and Krzysztof Książek
    Citation: Cellular & Molecular Biology Letters 2021 26:44
  24. Keratinocytes and fibroblasts represent the major cell types in the epidermis and dermis of the skin and play a significant role in maintenance of skin homeostasis. However, the biological characteristics of k...

    Authors: Tiancheng Wang, Zhenwei Zhou, Enjing Luo, Jinghong Zhong, Daqing Zhao, Haisi Dong and Baojin Yao
    Citation: Cellular & Molecular Biology Letters 2021 26:42
  25. More powerful prognostic and diagnostic tools are urgently needed for identifying and treating ovarian cancer (OC), which is the most fatal malignancy in women in developed countries. Circular RNAs (circRNAs) ...

    Authors: Zahra Foruzandeh, Fatemeh Zeinali-Sehrig, Kazem Nejati, Dara Rahmanpour, Fariba Pashazadeh, Farhad Seif and Mohammad Reza Alivand
    Citation: Cellular & Molecular Biology Letters 2021 26:41
  26. Endothelial cell (EC) injury accelerates the progression of diabetic macrovascular complications. Hypoxia is an important cause of EC injury. Hypoxia-inducible factor-1 alpha (HIF-1α) is an important hypoxia r...

    Authors: Min Zhao, Shaoting Wang, Anna Zuo, Jiaxing Zhang, Weiheng Wen, Weiqiang Jiang, Hong Chen, Donghui Liang, Jia Sun and Ming Wang
    Citation: Cellular & Molecular Biology Letters 2021 26:40
  27. Neurological disorders are considered one of the greatest burdens to global public health and a leading cause of death. Stem cell therapies hold great promise for the cure of neurological disorders, as stem ce...

    Authors: Michal Arad, Robert A. Brown, Raju Khatri, Rodney J. Taylor and Michal Zalzman
    Citation: Cellular & Molecular Biology Letters 2021 26:38
  28. Iron overload can promote the development of osteoporosis by inducing apoptosis in osteoblasts. However, the mechanism by which miRNAs regulate apoptosis in osteoblasts under iron overload has not been elucida...

    Authors: Yi Feng, Pei-Yan He, Wei-Dong Kong, Wan-Jing Cen, Peng-Lin Wang, Chang Liu, Wu Zhang, Shu-Shu Li and Jian-Wei Jiang
    Citation: Cellular & Molecular Biology Letters 2021 26:37
  29. Inflammatory bowel disease (IBD) is a kind of intestinal immune dysfunction disease, and its occurrence and prevalence are on the rise worldwide. As a chronic gastrointestinal disease, its pathogenesis is stil...

    Authors: Jing Shao, Yan Jin, Chunhong Shao, Hui Fan, Xiaorui Wang and Guang Yang
    Citation: Cellular & Molecular Biology Letters 2021 26:36
  30. Alkannin-based pharmaceutical formulations for improving wound healing have been on the market for several years. However, detailed molecular mechanisms of their action have yet to be elucidated. Here, we i...

    Authors: Xiao Yang, Weijing Fan, Renyan Huang and Guobin Liu
    Citation: Cellular & Molecular Biology Letters 2021 26:35
  31. Burn injury is one of the potential causes of heterotopic ossification (HO), which is a rare but debilitating condition. The incidence ranges from 3.5 to 5.6 depending on body area. Burns that cover a larger p...

    Authors: Xianglin Hu, Zhengwang Sun, Fengfeng Li, Chaoyin Jiang, Wangjun Yan and Yangbai Sun
    Citation: Cellular & Molecular Biology Letters 2021 26:34
  32. Long noncoding RNA (lncRNA), urothelial carcinoma-associated 1 (UCA1) is aberrantly expressed in multiple cancers and has been verified as an oncogene. However, the underlying mechanism of UCA1 in the developm...

    Authors: An Yang, Xin Liu, Ping Liu, Yunzhang Feng, Hongbo Liu, Shen Gao, Limin Huo, Xinyan Han, Jurong Wang and Wei Kong
    Citation: Cellular & Molecular Biology Letters 2021 26:33
  33. In the past decade, G protein-coupled receptors have emerged as drug targets, and their physiological and pathological effects have been extensively studied. Among these receptors, GPR119 is expressed in multi...

    Authors: Jianan Zhao, Yu Zhao, Yiyang Hu and Jinghua Peng
    Citation: Cellular & Molecular Biology Letters 2021 26:32
  34. Phenotypic and functional heterogeneity of macrophages is known to be the main reason for their ability to regulate inflammation and promote tumorigenesis. Mesenchymal stem cells (MSCs) are one of the principa...

    Authors: Shabnam Babazadeh, Seyed Mahdi Nassiri, Vahid Siavashi, Mohadeseh Sahlabadi, Mostafa Hajinasrollah and Mohamad Zamani-Ahmadmahmudi
    Citation: Cellular & Molecular Biology Letters 2021 26:30
  35. Activation of autophagy is part of the innate immune response during viral infections. Autophagy involves the sequestration of endogenous or foreign components from the cytosol within double-membraned vesicles...

    Authors: Päivi Ylä-Anttila
    Citation: Cellular & Molecular Biology Letters 2021 26:29
  36. Currently, resistance against cisplatin (DDP) is a frequent problem for the success of advanced gastric carcinoma (GC) chemotherapy. Here, we sought to investigate the function of activating transcription fact...

    Authors: Dazhi Fu, Chunxiao Wang, Lei Yu and Rui Yu
    Citation: Cellular & Molecular Biology Letters 2021 26:26
  37. Diabetic nephropathy is one of the most important complications in patients with diabetes. The etiology and pathogenesis of diabetic nephropathy remain unclear. Several studies have indicated that circular RNA...

    Authors: Xuan Xiong, Changchun Liu, Meiren Shen, Qian Yang, Qiang Zhao, Xiaoyan Li, Xiaoshi Zhong and Zhiwei Wang
    Citation: Cellular & Molecular Biology Letters 2021 26:25
  38. The suppressive effects of miR-33a-5p have been reported in colorectal cancer and lung cancer. However, the functional role of miR-33a-5p in pancreatic ductal adenocarcinoma (PDAC) has not yet been elucidated.

    Authors: Yanfen Lian, Dongxiao Jiang and Jiangtao Sun
    Citation: Cellular & Molecular Biology Letters 2021 26:24
  39. Manganese overexposure can induce neurotoxicity, lead to manganism and result in clinical manifestations similar to those of parkinsonism. However, the underlying molecular mechanism is still unclear. This stu...

    Authors: Yanning Huang, Qiaolin Wen, Jinfeng Huang, Man Luo, Yousheng Xiao, Ruikang Mo and Jin Wang
    Citation: Cellular & Molecular Biology Letters 2021 26:23
  40. Improved chondrogenic differentiation of mesenchymal stem cells (MSCs) by genetic regulation is a potential method for regenerating articular cartilage. MiR-127-5p has been reported to promote cartilage differ...

    Authors: Xiaozhong Zhou, Wangyang Xu, Yeyang Wang, Hui Zhang, Li Zhang, Chao Li, Shun Yao, Zixiang Huang, Lishan Huang and Dixin Luo
    Citation: Cellular & Molecular Biology Letters 2021 26:22
  41. Recently, pivotal functions of miRNAs in regulating common tumorigenic processes and manipulating signaling pathways in brain tumors have been recognized; notably, miR‐29a is closely associated with p53 signal...

    Authors: Qiudan Chen, Weifeng Wang, Shuying Chen, Xiaotong Chen and Yong Lin
    Citation: Cellular & Molecular Biology Letters 2021 26:21

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