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  1. The testicular receptor 4 (TR4) is a member of the nuclear receptor superfamily that controls various biological activities. A protective role of TR4 against oxidative stress has recently been discovered. We h...

    Authors: Shian-Jang Yan, Yi-Fen Lee, Huei-Ju Ting, Ning-Chun Liu, Su Liu, Shin-Jen Lin, Shauh-Der Yeh, Gonghui Li and Chawnshang Chang
    Citation: Cellular & Molecular Biology Letters 2012 17:12
    Content type: Research Article Published on:

  2. To explore the role of the integrin signaling pathway in hepatocytes during rat liver regeneration, the integrin signaling pathway-related gene expression profile in hepatocytes of regenerative liver was detec...

    Authors: Cunshuan Xu, Yanjie Yang, Junying Yang, Xiaoguang Chen and Gaiping Wang
    Citation: Cellular & Molecular Biology Letters 2012 17:11
    Content type: Short Communication Published on:

  3. Anthocyanins are one of the main flavonoid groups. They are responsible for, e.g., the color of plants and have antioxidant features and a wide spectrum of medical activity. The subject of the study was the fo...

    Authors: Dorota Bonarska-Kujawa, Hanna Pruchnik and Halina Kleszczyńska
    Citation: Cellular & Molecular Biology Letters 2012 17:10
    Content type: Research Article Published on:

  5. Aqueous-saline human placenta extract (HPE) is known to possess antioxidant activity due to the high concentration of bioactive substances. This fact allows its application in clinical practice in order to tre...

    Authors: Svitlana Rozanova, Yana Cherkashina, Svitlana Repina, Katherina Rozanova and Oleg Nardid
    Citation: Cellular & Molecular Biology Letters 2012 17:7
    Content type: Research Article Published on:

  8. Preservation of hepatocyte functions in vitro will undoubtedly help the management of acute liver failure. The coculture system may be able to prevent functional decline of hepatocytes. It has already been shown ...

    Authors: Xia Chen, Shichang Zhang, Tao Liu, Yong Liu and Yingjie Wang
    Citation: Cellular & Molecular Biology Letters 2012 17:4
    Content type: Research Article Published on:

  9. Highly concentrated urine may induce a harmful effect on the urinary bladder. Therefore, we considered osmolarity of the urine as a basic pathomechanism of mucosal damage. The influence of both cyclophosphamid...

    Authors: Kajetan Juszczak, Jolanta Kaszuba-Zwoińska, Paulina Chorobik, Agata Ziomber and Piotr Jan Thor
    Citation: Cellular & Molecular Biology Letters 2012 17:2
    Content type: Short Communication Published on:

  11. Inositol 1,4,5-trisphosphate receptor type 1 (IP3R1) is already known to be highly expressed in the brain, and is found in many other tissues, including the atrium of the heart. Although the complete primary stru...

    Authors: Krishna P. Subedi, Thoudam Debraj Singh, Joon-Chul Kim and Sun-Hee Woo
    Citation: Cellular & Molecular Biology Letters 2011 17:43
    Content type: Short Communication Published on:

  12. Biogenic membranes or self-synthesizing membranes are the site of synthesis of new lipids such as the endoplasmic reticulum (ER) in eukaryotes. Newly synthesized phospholipids (PLs) at the cytosolic leaflet of...

    Authors: Archita Rajasekharan and Sathyanarayana N. Gummadi
    Citation: Cellular & Molecular Biology Letters 2011 17:42
    Content type: Research Article Published on:

  13. Virus-induced gene silencing is an important tool for functional gene analysis and the vector based on Barley stripe mosaic virus (BSMV) is widely used for the purpose in monocots. Of the tripartite BSMV genome, ...

    Authors: Adam Kawalek, Marta Dmochowska-Boguta, Anna Nadolska-Orczyk and Waclaw Orczyk
    Citation: Cellular & Molecular Biology Letters 2011 17:41
    Content type: Research Article Published on:

  14. The emerging fields of tissue engineering and biomaterials have begun to provide potential treatment options for liver failure. The goal of the present study is to investigate the ability of a poly L-lactic ac...

    Authors: Mahboobe Ghaedi, Masoud Soleimani, Iman Shabani, Yuyou Duan and Abbas S. Lotfi
    Citation: Cellular & Molecular Biology Letters 2011 17:40
    Content type: Research Article Published on:

  15. P5 ATPases (ATP13A1 through ATP13A5) are found in all eukaryotes. They are currently poorly characterized and have unknown substrate specificity. Recent evidence has linked two P5 ATPases to diseases of the nervo...

    Authors: Lisa S. Weingarten, Hardi Dave, Hongyan Li and Dorota A. Crawford
    Citation: Cellular & Molecular Biology Letters 2011 17:39
    Content type: Research Article Published on:

  16. The purpose of these studies was to determine the effect of polyphenols contained in extracts from apple, strawberry and blackcurrant on the properties of the erythrocyte membrane, treated as a model of the bi...

    Authors: Sylwia Cyboran, Jan Oszmiański and Halina Kleszczyńska
    Citation: Cellular & Molecular Biology Letters 2011 17:38
    Content type: Short Communication Published on:

  17. Diphtheria toxin (DT) and its N-terminal fragment A (FA) catalyse the transfer of the ADP-ribose moiety of nicotinamide adenine dinucleotide (NAD) into a covalent linkage with eukaryotic elongation factor 2 (e...

    Authors: Başak Varol, Muhammet Bektaş, Rüstem Nurten and Engin Bermek
    Citation: Cellular & Molecular Biology Letters 2011 17:36
    Content type: Research Article Published on:

  18. Tumor establishment and penetration consists of a series of complex processes involving multiple changes in gene expression and protein modification. Proteome changes of tumor tissue were investigated after in...

    Authors: Jihye Lee, Gunsup Lee, Jin Hee Park, Sukchan Lee, Chang-Hwan Yeom, Byungjo Na and Seyeon Park
    Citation: Cellular & Molecular Biology Letters 2011 17:35
    Content type: Research Article Published on:

  19. Thy28 protein is conserved among plants, bacteria, and mammalian cells. Nuclear Thy28 protein is substantially expressed in testis, liver, and immune cells such as lymphocytes. Lymphocyte apoptosis plays a cru...

    Authors: Hiroko Toyota, Xiao-Zhou Jiang, Hideki Asakura and Junichiro Mizuguchi
    Citation: Cellular & Molecular Biology Letters 2011 17:34
    Content type: Research Article Published on:

  20. Anucleated erythrocytes were long considered as oxygen-transporting cells with limited regulatory functions. Components of different nuclear signaling pathways have not been investigated in those cells, yet. S...

    Authors: Mehrdad Ghashghaeinia, Mahmoud Toulany, Mohammad Saki, H. Peter Rodemann, Ulrich Mrowietz, Florian Lang and Thomas Wieder
    Citation: Cellular & Molecular Biology Letters 2011 17:32
    Content type: Mini Review Published on:

  21. Dendrimers, highly branched macromolecules with a specific size and shape, provide many exciting opportunities for biomedical applications. However, most dendrimers demonstrate toxic and haemolytic activity be...

    Authors: Barbara Ziemba, Gabriela Matuszko, Maria Bryszewska and Barbara Klajnert
    Citation: Cellular & Molecular Biology Letters 2011 17:33
    Content type: Mini Review Published on:

  23. The evolutionarily-conserved protein phosphatase 1 (PP1) plays a central role in dephosphorylation of phosphoproteins during the M phase of the cell cycle. We demonstrate here that the PP1 inhibitor inhibitor-...

    Authors: Arian Khandani, Mahmood Mohtashami and Anne Camirand
    Citation: Cellular & Molecular Biology Letters 2011 16:669
    Content type: Research Article Published on:

  24. Recent results obtained in various crops indicate that real-time PCR could be a powerful tool for the detection and characterization of transgene locus structures. The determination of transgenic locus number ...

    Authors: Agata Gadaleta, Angelica Giancaspro, Maria Francesca Cardone and Antonio Blanco
    Citation: Cellular & Molecular Biology Letters 2011 16:652
    Content type: Research Article Published on:

  25. Kindlin-2 is a recently identified FERM and PH domain containing integrin interacting protein. Kindlin-2 is ubiquitously expressed in normal tissues. So far, much effort has been spent exploring the functional...

    Authors: Ammad Aslam Khan, Takashi Shimokawa, Staffan Strömblad and Hongquan Zhang
    Citation: Cellular & Molecular Biology Letters 2011 16:638
    Content type: Research Article Published on:

  26. The formation of aqueous intercellular channels mediating gap junctional intercellular coupling (GJIC) is a canonical function of connexins (Cx). In contrast, mechanisms of GJIC-independent involvement of conn...

    Authors: Katarzyna Szpak, Ewa Wybieralska, Ewa Niedziałkowska, Monika Rak, Iga Bechyne, Marta Michalik, Zbigniew Madeja and Jarosław Czyż
    Citation: Cellular & Molecular Biology Letters 2011 16:625
    Content type: Research Article Published on:

  27. This study aimed to determine the changes in the expression of genes for selected specific transcriptional factors that have both activating and repressing functions in in vitro ductal breast cancer cells, under ...

    Authors: Marta Ziaja-Sołtys and Jolanta Rzymowska
    Citation: Cellular & Molecular Biology Letters 2011 16:610
    Content type: Short Communication Published on:

  29. The interaction between a charged metal implant surface and a surrounding body fluid (electrolyte solution) leads to ion redistribution and thus to formation of an electrical double layer (EDL). The physical p...

    Authors: Ekaterina Gongadze, Ursula Van Rienen and Aleš Iglič
    Citation: Cellular & Molecular Biology Letters 2011 16:576
    Content type: Mini Review Published on:

  30. Osteoarthritis (OA) is the most common cause of musculoskeletal pain and disability. The importance of chondrocytes in the pathogenesis of OA is unequivocal. 17β-estradiol (E2) has a potential protective effec...

    Authors: Jia Gu Huang, Chun Xia, Xin Peng Zheng, Ting Ting Yi, Xiao Yong Wang, Gang Song and Bing Zhang
    Citation: Cellular & Molecular Biology Letters 2011 16:564
    Content type: Short Communication Published on:

  31. The protein ERp57/GRP58 is a stress-responsive protein and a component of the protein disulfide isomerase family. Its functions in the endoplasmic reticulum are well known, concerning mainly the proper folding...

    Authors: Carlo Turano, Elisa Gaucci, Caterina Grillo and Silvia Chichiarelli
    Citation: Cellular & Molecular Biology Letters 2011 16:539
    Content type: Review Published on:

  32. ReNcell VM is an immortalized human neural progenitor cell line with the ability to differentiate in vitro into astrocytes and neurons, in which the Wnt/β-catenin pathway is known to be involved. However, little ...

    Authors: Orianne Mazemondet, Rayk Hubner, Jana Frahm, Dirk Koczan, Benjamin M. Bader, Dieter G. Weiss, Adelinde M. Uhrmacher, Moritz J. Frech, Arndt Rolfs and Jiankai Luo
    Citation: Cellular & Molecular Biology Letters 2011 16:515
    Content type: Research Article Published on:

  33. Severe acute pancreatitis (SAP) is a common disease with a poor prognosis. Heart failure is one cause of SAP patient death. Intermedin (IMD) is a potent endogenous cardio-protective substance. Administration o...

    Authors: Xiaodong Du, Yu Cao, Ping Xue, Ziqi Lin, Zhi Zeng and Qing Xia
    Citation: Cellular & Molecular Biology Letters 2011 16:20
    Content type: Research Article Published on:

  35. The use of tissue-specific promoter elements in the treatment of cervical cancer has been explored in this paper. The P105 promoter of human papillomavirus 18 (HPV18) was utilised to direct tissue-specific expres...

    Authors: Mandy S. Y. Lung, Wendy M. Mak and Vincent Murray
    Citation: Cellular & Molecular Biology Letters 2011 16:18
    Content type: Research Article Published on:

  36. Yeast two-hybrid (Y2H) and isothermal titration calorimetry (ITC) methods were used to further study the mutational effect of non-erythroid alpha spectrin (αII) at position 22 in tetramer formation with beta s...

    Authors: Akin Sevinc, Marta A. Witek and Leslie W. -M. Fung
    Citation: Cellular & Molecular Biology Letters 2011 16:17
    Content type: Short Communication Published on:

  37. The ADAM (A Disintegrin and Metalloprotease) family of transmembrane proteins plays important roles in embryogenesis and tissue formation based on their multiple functional domains. In the present study, for t...

    Authors: Annett Markus, Xin Yan, Arndt Rolfs and Jiankai Luo
    Citation: Cellular & Molecular Biology Letters 2011 16:16
    Content type: Research Article Published on:

  38. Published data concerning the effects of hypertonicity on cell motility have often been controversial. The interpretation of results often rests on the premise that cell responses result from cell dehydration,...

    Authors: Włodzimierz Korohoda, Magdalena Kucia, Ewa Wybieralska, Magdalena Wianecka-Skoczeń, Agnieszka Waligórska, Justyna Drukała and Zbigniew Madeja
    Citation: Cellular & Molecular Biology Letters 2011 16:15
    Content type: Research Article Published on:

  39. We used a continuum model based on the Helfrich free energy to investigate the binding dynamics of a lipid bilayer to a BAR domain surface of a crescent-like shape of positive (e.g. I-BAR shape) or negative (e...

    Authors: Doron Kabaso, Ekaterina Gongadze, Jernej Jorgačevski, Marko Kreft, Ursula Van Rienen, Robert Zorec and Aleš Iglič
    Citation: Cellular & Molecular Biology Letters 2011 16:13
    Content type: Review Published on:

  40. The tight junction protein claudin-4 is frequently overexpressed in pancreatic cancer, and is also a receptor for Clostridium perfringens enterotoxin (CPE). The cytotoxic effects of CPE are thought to be useful a...

    Authors: Hiroshi Yamaguchi, Takashi Kojima, Tatsuya Ito, Daisuke Kyuno, Yasutoshi Kimura, Masafumi Imamura, Koichi Hirata and Norimasa Sawada
    Citation: Cellular & Molecular Biology Letters 2011 16:14
    Content type: Research Article Published on:

  42. Post-mitotic neurons are typically terminally differentiated and in a quiescent status. However, in Alzheimer disease (AD), many neurons display ectopic re-expression of cell cycle-related proteins. Cyclin-dep...

    Authors: Vladan P. Bajić, Bo Su, Hyoung-Gon Lee, Wataru Kudo, Sandra L. Siedlak, Lada Živković, Biljana Spremo-Potparević, Ninoslav Djelic, Zorana Milicevic, Avneet K. Singh, Lara M. Fahmy, Xinglong Wang, Mark A. Smith and Xiongwei Zhu
    Citation: Cellular & Molecular Biology Letters 2011 16:11
    Content type: Research Article Published on:

  43. Noncovalent DIDS binding to Band 3 (AE1) protein in human erythrocyte membranes, modified by non-penetrating, water soluble 1-ethyl-3-(4-azonia-4,4-dimethylpentyl)-carbodiimide iodide (EAC), was studied at 0°C...

    Authors: Teresa Janas and Tadeusz Janas
    Citation: Cellular & Molecular Biology Letters 2011 16:10
    Content type: Research Article Published on:

  44. The transcription factor p63 has important functions in tumorigenesis, epidermal differentiation and stem cell self-renewal. The TP63 gene encodes multiple protein isoforms that have different or even antagonisti...

    Authors: Marta Nekulova, Jitka Holcakova, Philip Coates and Borivoj Vojtesek
    Citation: Cellular & Molecular Biology Letters 2011 16:9
    Content type: Review Published on:

  45. Protein-protein interactions (PPI) control most of the biological processes in a living cell. In order to fully understand protein functions, a knowledge of protein-protein interactions is necessary. Predictio...

    Authors: Piyali Chatterjee, Subhadip Basu, Mahantapas Kundu, Mita Nasipuri and Dariusz Plewczynski
    Citation: Cellular & Molecular Biology Letters 2011 16:8
    Content type: Short communication Published on:

  46. We demonstrate here that distribution of caspase-9 influences the pathway of apoptosis triggering, since caspase-9 is activated efficiently only when it is distributed solely in the cytosol. Caspase-9 moves to...

    Authors: Blaž Banič, Damijan Nipič, Dušan Šuput and Irina Milisav
    Citation: Cellular & Molecular Biology Letters 2011 16:7
    Content type: Research Article Published on:

  47. This is a review of the growing scientific interest in the developmental plasticity and therapeutic potential of stromal cells isolated from adipose tissue. Adipose-derived stem/stromal cells (ASCs) are multip...

    Authors: Malgorzata Witkowska-Zimny and Katarzyna Walenko
    Citation: Cellular & Molecular Biology Letters 2011 16:5
    Content type: Review Published on:

  48. Studying the interactome is one of the exciting frontiers of proteomics, as shown lately at the recent bioinformatics conferences (for example ISMB 2010, or ECCB 2010). Distribution of data is facilitated by a...

    Authors: Dariusz Plewczynski and Tomas Klingström
    Citation: Cellular & Molecular Biology Letters 2011 16:4
    Content type: Short communication Published on:

  49. The activities of myogenic regulatory factors (MRF) and muscle growth factors increase in muscle that is undergoing regeneration, and may correspond to some specific changes. Little is known about the role of ...

    Authors: Alexander Spassov, Tomasz Gredes, Tomasz Gedrange, Silke Lucke, Dragan Pavlovic and Christiane Kunert-Keil
    Citation: Cellular & Molecular Biology Letters 2011 16:3
    Content type: Short Communication Published on:

  50. High aldosterone (Ald) levels can induce hypertrophy of vascular smooth muscle cells (VSMCs), which carries high risks of heart failure. A previous study showed that Ald induces hypertrophy of VSMCs by up-regu...

    Authors: Yanping Fu, Gang Shi, Yong Wu, Yasuyuki Kawai, Qing Tian, Linlin Yue, Qinjie Xia, Isamu Miyamori and Chunyuan Fan
    Citation: Cellular & Molecular Biology Letters 2011 16:2
    Content type: Research Article Published on:

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